Python is widely used in Mathematical Programming as a modeling language.
In commercial products, Gurobi has built its interactive shell in Python.
In open source world, Pyomo from Sandia National Lab use Python to offer an AMPL-like modeling language. Pyomo uses GLPK solver by default, but other solvers, such as GLPK, Gurobi, COIN CBC, can also be selected.
GLPK (GNU Linear Programming Toolkit) supports MathProg, which is also referred as GMPL (GNU Mathematical Programming Language). GLPK provides a command line tool glpsol, which is convenient for users to solve various optimization problems with well designed reports.
PuLP is an LP modeler written in Python. PuLP can generate MPS or LP files, and can call GLPK, COIN CLP.CBC, CPLEX and Gurobi to solve linear problems.
SolverStudio makes it easy to develop models inside Excel using Python. Data entered into the spreadsheet is automatically available to the model. SolverStudio supports PuLP, COOPR/Pyomo, AMPL, GMPL, GAMS, Gurobi, CMPL, SimPy.